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| Peracchi,O.A.B.; Terreri,M.T.R.A.; Munekata,R.V.; Len,C.A.; Sarni,R.O.S.; Lazaretti-Castro,M.; Hilário,M.O.E.. |
| We evaluated the concentrations of 25-hydroxyvitamin D [25(OH)D] in children and adolescents with juvenile systemic lupus erythematosus (JSLE) and associated them with disease duration and activity, use of medication (chloroquine and glucocorticoids), vitamin D intake, calcium and alkaline phosphatase levels, and bone mineral density. Thirty patients with JSLE were evaluated and compared to 30 healthy individuals, who were age and gender matched. Assessment was performed of clinical status, disease activity, anthropometry, laboratory markers, and bone mineral density. The 30 patients included 25 (83.3%) females and 16 (53.3%) Caucasians, with a mean age of 13.7 years. The mean age at diagnosis was 10.5 years and mean disease duration was 3.4 years. Mean... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Juvenile systemic lupus erythematosus; Vitamin D; Calcium; Bone metabolism; Parathormone. |
| Ano: 2014 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2014000800721 |
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| Faco,M.M.M.; Leone,C.; Campos,L.M.A.; Febrônio,M.V.; Marques,H.H.S.; Silva,C.A.. |
| We assessed the risk factors associated with death in patients hospitalized for juvenile systemic lupus erythematosus (JSLE) and evaluated the autopsy reports. A total of 57,159 hospitalizations occurred in our institution from 1994 to 2003, 169 of them involving 71 patients with JSLE. The most recent hospitalization of these patients was evaluated. Patients were divided into two groups based on mortality during hospitalization: those who survived (N = 53) and those who died (N = 18). The main causes of hospitalization were JSLE activity associated with infection in 52% and isolated JSLE activity in 44%. Univariate analysis showed that a greater risk of death was due to severe sepsis (OR = 17.8, CI = 4.5-70.9), systemic lupus erythematosus disease activity... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Juvenile systemic lupus erythematosus; Hospitalization; Outcome; Autopsy; Severe sepsis; Infection. |
| Ano: 2007 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2007000700015 |
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